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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGL All Species: 22.12
Human Site: T1185 Identified Species: 44.24
UniProt: P35573 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35573 NP_000019.2 1532 174764 T1185 P V S R M Y P T D D S A P L P
Chimpanzee Pan troglodytes XP_524777 1532 174746 T1185 P V S R M Y P T D D S A P L P
Rhesus Macaque Macaca mulatta XP_001106231 1532 174684 T1185 P V S R M Y P T D D S A P L P
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus NP_001074795 1532 174269 T1185 P V S R M Y P T D D S A P L P
Rat Rattus norvegicus NP_001102034 1532 174314 T1185 P V S R M Y P T D D S A P L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512323 1163 131293 Q856 R E K N A G P Q I D R N M K D
Chicken Gallus gallus XP_422317 1532 174660 R1185 P V S R M Y P R D D S A P Q P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_696194 1052 117860 Q745 R E S N A G P Q I D R N M R D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_726062 1629 183200 Q1305 D V M Q E A L Q V H F Q G L Q
Honey Bee Apis mellifera XP_394961 1549 176545 T1184 K V S R L F P T D D S P P L P
Nematode Worm Caenorhab. elegans NP_496984 1467 165910 K1154 T I Y E A L D K H F A G I D Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06625 1536 174953 R1198 I I Y E I L S R H A K G I K F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 97.6 N.A. N.A. 91.9 92.1 N.A. 67.6 81.7 N.A. 53.3 N.A. 45.2 49.9 44.2 N.A.
Protein Similarity: 100 100 99.2 N.A. N.A. 96.6 96.4 N.A. 72 91.5 N.A. 61.3 N.A. 61.4 66.6 62 N.A.
P-Site Identity: 100 100 100 N.A. N.A. 100 100 N.A. 13.3 86.6 N.A. 20 N.A. 13.3 73.3 0 N.A.
P-Site Similarity: 100 100 100 N.A. N.A. 100 100 N.A. 13.3 86.6 N.A. 20 N.A. 20 86.6 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 35.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 52.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 25 9 0 0 0 9 9 50 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 0 9 0 59 75 0 0 0 9 17 % D
% Glu: 0 17 0 17 9 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 9 0 0 0 9 9 0 0 0 9 % F
% Gly: 0 0 0 0 0 17 0 0 0 0 0 17 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 17 9 0 0 0 0 0 % H
% Ile: 9 17 0 0 9 0 0 0 17 0 0 0 17 0 0 % I
% Lys: 9 0 9 0 0 0 0 9 0 0 9 0 0 17 0 % K
% Leu: 0 0 0 0 9 17 9 0 0 0 0 0 0 59 0 % L
% Met: 0 0 9 0 50 0 0 0 0 0 0 0 17 0 0 % M
% Asn: 0 0 0 17 0 0 0 0 0 0 0 17 0 0 0 % N
% Pro: 50 0 0 0 0 0 75 0 0 0 0 9 59 0 59 % P
% Gln: 0 0 0 9 0 0 0 25 0 0 0 9 0 9 9 % Q
% Arg: 17 0 0 59 0 0 0 17 0 0 17 0 0 9 0 % R
% Ser: 0 0 67 0 0 0 9 0 0 0 59 0 0 0 0 % S
% Thr: 9 0 0 0 0 0 0 50 0 0 0 0 0 0 0 % T
% Val: 0 67 0 0 0 0 0 0 9 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 17 0 0 50 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _